News

BEAT BioTherapeutics Corporation closes $2.5MM Seed Financing to develop its gene therapy treatment for heart failure? April 16th, 2013

BEAT BioTherapeutics Corporation appoints Michael Kranda as CEO April 15th, 2013

Gene therapy may aid failing hearts – UW Medicine article, March 26, 2025

UW Researchers see work as step toward regenerating human heart - Seattle Times article, Aug 7, 2025

 

Papers/publications:

Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation.

J Mol Cell Cardiol. 2011 Dec;51(6):894-901.

Korte FS, Dai J, Buckley K, Feest ER, Adamek N, Geeves MA, Murry CE, Regnier M.

Transgenic overexpression of ribonucleotide reductase improves cardic performance.

Proc Natl Acad Sci U S A. 2013 Mar 25

Nowakowski SG, Kolwicz SC, Korte FS, Luo Z, Robinson-Hamm JN, Page JL, Brozovich F, Weiss RS, Tian R, Murry CE, Regnier M.

Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts.

Shiba Y, Fernandes S, Zhu WZ, Filice D, Muskheli V, Kim J, Palpant NJ, Gantz J, Moyes KW, Reinecke H, Van Biber B, Dardas T, Mignone JL, Izawa A, Hanna R, Viswanathan M, Gold JD, Kotlikoff MI, Sarvazyan N, Kay MW, Murry CE, Laflamme MA.

Refueling the heart: Using 2-deoxy-ATP to enhance cardiac contractility. Baker AJ.

J Mol Cell Cardiol. 2011 Dec;51(6):883-4.